As your contract synthesis partner, we provide a one-stop CDMO service spanning everything from sample synthesis and early-stage development to scale-up and commercial production at up to 15,000 L. With extensive facilities and years of accumulated expertise, we help solve every challenge in outsourced manufacturing.
Benefit from our proven track record of supporting the manufacturing and development of over 700 companies.
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- Agrochemical Active Ingredients and Intermediates — Highly demanding synthesis built on our core halogenation technology, backed by extensive experience in agrochemical CDMO
- Pharmaceutical Active Ingredients and Intermediates — High-quality manufacturing under cGMP control, with a proven track record of passing regulatory audits worldwide
- Electronic Materials — Contract manufacturing of high-performance materials with precision organic synthesis and rigorous impurity control
- High-Performance Fine Chemicals — Flexible CDMO services supporting a wide range of products and production scales
Learn more about our CDMO services in each field:
Agrochemical CDMO
Small Molecule CDMO
High-Performance Chemicals CDMO
We possess a broad range of synthesis and purification technologies, led by advanced fluorination (halogenation) technology. Our core strength is a proprietary scale-up technology that safely and efficiently translates lab-scale findings into large-scale, ton-scale equipment.
- Halogenation reactions (F, Cl, Br, and I all supported)
- Ultra-low temperature reactions (down to ~−100°C), high-temperature reactions (up to ~250°C), and pressurized reactions (up to ~0.6 MPa)
- Grignard reactions and various cross-coupling reactions (Suzuki, Buchwald, and others)
- Precision distillation (up to ~40 stages), crystallization, thin-film distillation, and drying
- Iodine recovery and recycling technology, in partnership with our group company Ise Chemicals
See our full list of supported reactions →
From early-stage process development through pilot-scale trial production, our experienced R&D team responds quickly and proposes the optimal manufacturing process for scale-up to commercial production.
- Development of New Synthetic Routes — Designing optimal routes from scratch using literature review and our proprietary databases
- Scale-Up Studies — Smooth technology transfer from lab to pilot to commercial production
- Close Collaboration Between R&D and Manufacturing — Rapidly building robust processes designed for large-scale production
- Regulatory Application Support — One-stop support for complex filings, including under the Chemical Substances Control Law and the Industrial Safety and Health Act
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We handle contract development and synthesis of new compounds tailored to your needs. Once your target compound is defined, we support you end-to-end—from desk study and preliminary cost estimation through trial and commercial production.
- Detailed discussions following execution of a Non-Disclosure Agreement (NDA)
- Literature review and new synthetic route design (available from a zero base)
- One-stop support from laboratory study through scale-up to commercial production
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Our in-house facilities range from small-scale equipment for kilogram-class synthesis to ton-scale and large reactors of up to 15,000 L, meeting a wide range of scale-up needs.
- Reactor materials: Glass-Lined (GL), Stainless Steel (SUS), and Hastelloy (HC)
- Temperature range: from ultra-low temperatures (−40°C) to high temperatures (250°C)
- Pressurized reactions: up to 0.6 MPa
- Purification equipment: precision distillation (up to ~40 stages), thin-film distillation, crystallization, and drying
- Analytical instruments: a wide range of equipment including HPLC, GC, NMR, LC-MS, ICP-MS, and XRD
See details of our facilities and locations →
- ISO 9001 certified (AGC Wakasa Chemical)
- Operating a Quality Management System (QMS) aligned with global standards
- Rigorous control of impurities and lot-to-lot consistency
- In-process quality assured using a wide range of analytical instruments, including HPLC, GC, NMR, and LC-MS
- Continuously supplying high-quality products trusted by more than 110 companies across diverse industries
We have maintained an extremely low quality deviation lot rate from 2008 through 2025.
- ISO 14001 certified (AGC Wakasa Chemical)
- Ongoing investment in sustainability aimed at reducing our impact on the global environment
- Optimal waste treatment processes established for each manufacturing process
- Reduced costs and improved sustainability through the regeneration and recycling of waste isomers
- Installation and operation of advanced environmental equipment that goes beyond regulatory compliance
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AGC Wakasa Chemical (Fukui Prefecture) operates two plants as our manufacturing and development sites.
Obama Plant (Head Office)
A production system built around compact equipment, offering flexible responsiveness to a wide range of products and needs.
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Kaminaka Plant
Supporting scales from 100 L up to 15,000 L, equipped with specialized equipment such as Hastelloy reactors and multi-stage distillation columns.
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See details of our facilities and locations →
Specialized technical staff across process development plant-scale manufacturing quality control/assurance (QC/QA) and environmental and safety management collaborate to drive each project forward.
- Process Development Team — Handles synthetic route design scale-up and regulatory filings
- Manufacturing Team — Plant-scale manufacturing process control and final optimization of manufacturing conditions
- QC/QA Team — Analysis quality assurance and response to regulatory audits worldwide
- Sourcing Team — Securing a reliable raw material supply through our global network
- Environmental and Safety Management Team — Regulatory compliance environmental protection and business continuity planning (BCP)
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We have built a network for the reliable procurement of raw materials, leveraging our proprietary global sourcing network. From a business continuity planning (BCP) perspective as well, we provide a robust and dependable supply chain and manufacturing structure.
- Global Sourcing Bases — Diversified sourcing leveraging our own bases in China, India, and Europe
- On-Site Audits by Dedicated Chemical Engineers — Ensuring the reliability of overseas suppliers through QCD+EHS audits
- Reliable Procurement and Recycling of Iodine — In partnership with our group company Ise Chemicals Co., Ltd., one of the leading iodine suppliers in the world
- AGC Proprietary Chemical Chain — Leveraging our integrated production strength, from basic chemicals to high-performance fine chemicals
Sourcing Framework → Synthesis Track Record
Scale-up, Fluorination, Halogenation, Agrochemical Intermediates, Pharmaceutical Intermediates, Electronic Materials
- - 1-5-1 Marunouchi, Chiyoda-ku, Tokyo, 100-0005
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