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100000000yen
Osaka Small and Medium Business Investment & Consultation Co., Ltd
133
3.6 billion yen (in 2019)
Small scale production / Oxidation, Heavy metal compound / No-pressure distillation / High temperature reaction (over 200 C degree) / Radical polymerization / Drying, (No-pressure/Vacuum) / Hydrogenation / Bromination / Ullman reaction / Enzymatic reaction / Inorganic compound / Peptide synthesis / Peptide synthesis / Synthesis of chemical reagent and pharmaceutical intermediate / Preparative crude refining / Optical microscope / Nuclear magnetic resonance spectrometry(NMR) / Differential scanning calorimetry(DSC) / Liquid chromatography analysis（LC） / Color difference / Synthesis of medicinal standard product / Metallic sodium, Metallic potassium / Hydrogen cyanide, Sodium cyanide, Potassium cyanide / Reduction, Nitro compound / Azidation / Mizoroki-Heck reaction / Kumada-Tamao-Corriu cross coupling / Flow synthesis / Oxidation, Peroxide / Vacuum distillation / Reduction, Metalic hydride / Low temperature reaction (over -20 C degree) / Photochemical reaction / Anionic polymerization / Chlorination / Nitration / Acylation / Organic lithium / Oganic sulfur compound / Chiral synthesis / Chromatography / Carbohydrate synthesis / Purification, Preparative Isolation / Inductively coupled plasma-atomic emission spectrometry / Differential thermal analysis(DTA) / Gas chromatography analysis / Karl Fischer moisture analysis / Specific gravity / Synthesis of standard substance, medicinal metabolite / Others / freeze-drying / Negishi cross coupling / Glaser reaction / Dispersion / Rectification / Reduction, Catalytic / High-pressure reaction / Cationic polymerization / Column purification / Emulsification / High-pressure hydrolysis / Fluorination / Diazotization / Grignard reaction / Optical resolution / Ultrafine Grinding(<10μm) / Glycopeptide synthesis / Synthesis of standard substance control / Head Space Gas Chromatography(HS/GC) / Organosilicon compound / Acetalization / Migita-Kosugi-Stille cross coupling / Reaction, Low boiling point-solvent / Hydrogeneration / Oxidization, Air / Living polymerization / Iodination / Acid chlorides / Reaction, NaNH2 / Acetylenic chemistry / High potency active (HPA) manufacturing / DNA/RNA synthesis / Carbon disulfide / Thin film distillation / Ultraviolet-Visible spectrophotometer(UV-VIS) / Liquid chromatography analysis-mass spectrometry(LC-MS) / Drying capacity / Synthesis of stable isotope labeled compound / Thermogravimetric analysis(TG) / Diazo-coupling reaction / Others / Diazocoupling / Sonogashira-Hagihara Cross Coupling / Polycondensation / Oxidization, Halogenide / Steam distillation / Fluorine compound / Reaction, NaH / Suzuki-Miyaura cross coupling / Production of small molecule cytotoxics / Bioscience / Sandmeyer reaction / Infrared spectroscopy(IR) / Gas chromatography analysis-mass spectrometry(GC-MS) / Viscosity / Synthesis of pesticide metabolite / Halogenate, Diverse halogenating agents / Mercaptan / Reaction, Special medium(liquid ammonia etc) / Dehydrogenation / Reduction, High/Middle-pressure / Emulsion polymerization / Sulfonation / Organic sodium / Phosgenation / Phosphoric compound / Production of pharmaceuticals/cosmetics / Sublimation / Others / Particle size distribution / Halogenate, Thionyl chloride, Sulfuryl chloride etc / Amidination / Buchwald-Hartwig cross coupling / Oxidation, Swern / Suspension polymerization / Extraction / Amination / Other organometal / Gas absorption / Custom research / Thiophosgene / X-ray diffraction(XRD) / Reaction under special circumstances / Halogenate, NCS, NBS, NCI etc / Chlorosulfonation / Peptide synthesis / Oxidation, Ozone / Solution polymerization / Crystallization / Others, Halogenation / Ethylene oxide / Ion chromatography(IC) / Optical rotation / Sulfonamidation / Chiral compound / Allylation / Oxidation, Nitric acid / Reduction, Birch / Reaction with bad smell substances / Solid Phase polymerization / Optical resolution / Alkylation / Flexibility / Gel permation chromatography(GPC) / Nitrosation / Reaction, Toxic substances / Electrolytic oxidation / Depolymerization / Coupling reaction / Wolff-Kishner-reduction / Absorption/Ion exchange / Aldol reaction / Thin layer chromatograph(TLC) / Fusing point / Oxidation, Jones / Reduction, Na/Li / Others / Membrance separation / Gel filtration chromatography(GFC) / Recrystallization / Wittig reaction / Oppenauer oxidation / Filtration / Etherfication / Baeyer-Villiger oxidation / Metal contents reduction / Esterification / Epoxidation / Oximation / Carbonylation / Cannizarro reaction / Guanidination / Knoevenagel condensation / Kolbe-Schmitt reaction / Silylation / Schiemann reaction / Strecker reaction / Diels-Alder / Tishchenko reaction / Cyanation / Perkin reaction / Hydroxyethylation / Hydroxymethylation / Hydroxylation / Vilsmeier reaction / Fries rearrangement / Friedel-Crafts reaction / Hoesch reaction / Hofmann's Reaction / Formylation / Michael addition / Mannich reaction / Methylolation / Racemization / Leuckart reaction / Cyclization / Ring-Opening reaction / Dealkylation / Dehalogenation / Dehydration / Rearrangement / Acid amide / Dehydrogenation / Decarbonation / Quaternarization of Amine, Benzyl oxide / Microorganism, Fermentation/Enzymatic /
Since our establishment in 1972, as a specialty chemical R&D contract research company, NARD Institute, Ltd. has been mainly engaged in two activities-the"synthesis of fine chemicals" and "development of functional materials"-to meet our clients'specific needs.
In addition, our subsidiary company, NARD Chemicals Ltd., based on the quality assurance system including GMPs and ISO 9002, has been providing trial chemicals and various types of products.
NARD Institute, Ltd.: CONTRACT RESEARCH, CUSTOM CHEMISTRY & PROCESS DEVELOPMENT
In contract manufacturing, we perform the following flexibly and intensively:
Development of process schemes, Optimization of process configuration,
Process condition setting and Engineering designs such as basic quality design.
As a concrete example, we can complete synthesis of a compound for which a synthetic approach has not yet been developed, or synthesis of compounds with special functions such as the denaturation of a polymer (including adhesives, paints, polymer films and others).
NARD Chemicals, Ltd.: CUSTOM MANUFACTURING
In response to such engineering designs from NARD Institute, Ltd., all our production, based on quality assurance, is performed accurately through close liaison between the production and technological departments (from several Kg to several tons in quantity).
Various types of reactions, removal and purification techniques, and techniques for test analysis −all these have already been sufficiently accumulated to support specific reactions, such as photoreaction, ozone reaction, electrolysis reaction and others.
Metal Nanoparticles: we have successfully developed metal nanoparticles for nanotech material (copper, platinum, iron and other metals).
Sublimation Purification Services: we have started contract purification services as the best purification method for organic EL materials.
NARD Institute, Ltd.:
Our facilities can be applied to any of the specific organic syntheses mentioned above and are applicable to a wide range of fields.
NARD Chemicals, Ltd.:
Reaction vessels 50−3000 L, Chromatographic separation equipment,and Clean rooms (class10000) have been installed.
NARD Chemicals, Ltd.:
Our quality assurance systems have been accomplished by the c-GMPs and the study drug GMPs under the manufacturer's license and by ISO9002 certification and other certifications (NARD Chemicals, Ltd. complies with FDA requirements).
Both NARD Institute, Ltd. and NARD Chemicals, Ltd. have already improved their own environment-related equipment, and equipment for disaster safety and sanitary affairs.
NARD Institute, Ltd.: Amagasaki City, Hyogo Pref.
NARD Chemicals, Ltd.: Sakai City, Osaka Pref.